Adult Still’s disease

Abstract

Adult Still’s Disease is a systemic inflammatory disease that manifests as a myriad of symptoms, the most frequent high-spiking
fever, a characteristic rash and arthralgias/arthritis. Although rare
it should be considered a cause of fever of unknown origin, and is
usually an exclusion diagnosis. Its aetiology is currently unknown;
genetic and various infectious agents have been suggested. The
clinical course can be divided in three main patterns: monophasic,
polycyclic and chronic. It should be kept in mind that acute and
chronic serious complications can be present. Treatment consists
in limiting the intensity of the symptoms through the use of aspirin
and NSAIDs and controlling its evolution with corticosteroids and
imunommodulating agents.