A gripe H5N1: o que saber e o que esperar

Ângela Bento; Tiago Tribolet de Abreu

Authors

Ângela Bento Serviço de Medicina 2 do Hospital do Espírito Santo-Évora
Tiago Tribolet de Abreu Serviço de Medicina 2 do Hospital do Espírito Santo-Évora

Keywords:

Influenza, influenza A virus, avian

Abstract

The infl uenza A (H5N1) virus, after the fi rst documented human
infection in 1997, has been responsible for a growing number of
cases in humans, especially since 2003. The increasing number
of cases and a mortality rate of 51%, has lead to fears that should
the virus acquire the ability to transmit from human to human, a
serious world pandemic of H5N1 infl uenza will occur.
In order to combat such an eventuality efforts have targeted
research and disease control in Asian countries where H5N1
infl uenza cases have been reported. It is possible that these efforts
are insuffi cient, and research for a H5N1 specifi c vaccine is being
pursued as well as other control measures. One of these measures
could be the use of antiviral therapy, such as oseltamivir, aiming
to reduce the severity and transmissibility of the disease.

Downloads

Download data is not yet available.

References

Osterholm MT. Preparing for the next pandemic. N Engl J Med 2005; 352: 1839-1842.

Hien TT, Jong M, Farrar J. Avian influenza – A challenge to global health care structures. N Engl J Med 2005; 351: 2363-2365.

http://www.who.int/csr/disease/influenza/H5N1-9reduit.pdf (acedido a 21 de Outubro de 2005).

Monto AS. The threat of an avian influenza pandemic. N Engl J Med 2005; 352: 323-325.

Treanor JJ. Influenza virus. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases; 6ª edição; Philadelphia: Elservier Churchill Livingstone 2005: 2060-2085.

http://www.cdc.gov/flu/avian/gen-info/facts.htm (acedido a 21 de Outubro de 2005).

http://www.cdc.gov/flu/avian/gen-info/transmission.htm (acedido a 21 de Outubro de 2005).

http://www.cdc.gov/flu/avian/gen-info/pandemics.htm (acedido a 21 de Outubro de 2005).

http://www.stanford.edu/group/virus/uda (acedido a 21 de Outubro de 2005).

http://www.who.int/csr/disease/avian_influenza/country/cases_table_2005_10_10/en/index.html (acedido a 21 de Outubro de 2005).

Ungchusak K, Auewarakul P, Dowell S et al. Probable person-to-person transmission of avian influenza A (H5N1). N Engl J Med 2005; 352: 333-340.

Hien TT, Liem NT, Dung NT et al. Avian influenza A (H5N1) in 10 patients in Vietnam. N Engl J Med 2004; 350: 1179-1188.

de Jong MD, Cam BV, Qui PT et al. Fatal avian influenza A (H5N1) in a child presenting with diarrhea followed by coma. N Engl J Med 2005; 352: 686-691.

http://www.cdc.gov/flu/avian/professional/han020405.htm (acedido a 21 de Outubro de 2005).

http://www.cdc.gov/flu/avian/professional/pdf/possible-exposure-avianflu.pdf (acedido a 21 de Outubro de 2005)

Carmo P. 2,5 milhões de doses para tratar pandemia de gripe. Diário de Notícias; 1 de Julho 2005.

http://www.who.int/csr/disease/avian_influenza/country/cases_table_2005_10_10/en/index.html (acedido a 21 de Outubro de 2005).

http://www.cdc.gov/travel/other/avian_influenza_se_asia_2005.htm (acedido a 21 de Outubro de 2005).

http://www.cdc.gov/flu/avian/professional/infect-control.htm (acedido a 21 de Outubro de 2005).

Stöhr K. Avian influenza and pandemics: research needs and opportunities. N Engl J Med 2005; 352. 405-407