Atrial fibrillation: rhythm control vs rate control
Keywords:
Atrial fibrillation, rhythm control, rate controlAbstract
Atrial fibrillation (AF) is the most common cardiac arrhythmia in
the clinical practice with increasing prevalence due to the population progressive aging. It is an important cause of morbidity and
mortality, especially that arising from cerebrovascular accident and heart failure.
The two main FA management concerns are to restore and/
or maintain sinus rhythm with pharmacologic and/or electrical
cardioversion, or to achieve satisfactory rate control, both with antithrombotic therapy.
Some studies have reported similar reduction of morbidity and
mortality when either of the treatments is applied.
When choosing the appropriate treatment there are a few
factors which must be taken into account such as the nature,
intensity and frequency of symptoms, comorbid conditions, patient
preferences and the response to the treatment.
This review will therefore focus on the potential risks and
benefits of these two strategies, identifying the better candidates
for each strategy as well as showing the current guidelines about these issues.
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Fuster V, Rydén LE, Cannom DS et al., ACC/AHA/ESC 2006 Guidelines for the management of patients with atrial fibrillation: full text. A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Eurospace 2006;8:651-745.
Jahangir A, Lee V, Priedman PA et al. Long-term progression and outcomes with aging in patients with lone atrial fibrillation: a 30-year follow-up study. Circulation 2007;115:3050.
Go AS, Hylek EM, Philips KA et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the Anticoagulation and Risk Factors in atrial fibrillation (ATRIA) Study. JAMA 2001;285:2370-2375.
Furberg CD, Psaty BM, Manolio TA et al. Prevalence of atrial fibrillation in elderly subjects. (the Cardiovascular Health Study). Am J Cardiol 1994; 74:236-241.
Bajpai A, Savelieva I, Camm AJ. Epidemiology and Economic Burden of Atrial Fibrillation. US Cardiovascular Disease 2007;14-17.
Miyasaka Y, Barnes ME, Gersh BJ et al. Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence. Circulation 2006;114:119.
Stewart S, Hart Cl, Hole DI et al. Population, prevalence, incidence and predictors of atrial fibrillation in the Renfrew/Paisley study. Heart 2001; 86:516-521.
Krahn AD, Manfreda J, Tate RB et al. The natural history of atrial fibrillation: incidence, risk factors, and prognosis in the Manitoba Follow-Up Study. Am J Med 1995;98:476-484.
Wolf P, Benjamin EJ, Belanger AJ et al. Secular trends in the prevalence of atrial fibrillation: The Framingham Study. Am Heart J 1996;131: 790-795.
Tsang TS, Miyasaka Y, Bames ME, Gersh BI. Epidemiological profile of atrial fibrillation: a contemporary perspective. Prog Cardiovas Dis 2005;48:1-8.
Levy S, Maarek M, Coumel P et al. Characterization of different subsets of atrial fibrillation in general practice in France: the ALFA study. The College of French Cardiologists. Circulation 1999;9:3028-3035.
Savelieva I, Camm AJ. Clinical relevance of silent atrial fibrillation: prevalence, prognosis, quality of life, and management. J Interv Card Electrophysiol 2000;4:369-382.
Wolf PA, Kannel WB, McGee DI, Meeks SL, Bharucha NE, MsNamara PM. Duration of atrial fibrillation and imminence of stroke: the Framingham Study. Stroke 1983;14:664-667.
Salieva I, Paquette M, Dorian P et al. Quality of life in patients with silent AF. Heart 2001;85:216-217.
Reynolds MR, Lavelle T, Essebag V et al. Influence of age, sex and atrial fibrillation recurrence on quality of life outcomes in a population of patients with new-onset atrial fibrillation: the Fibrillation Registry Assessing Costs, Therapies, Adverse events and Lifestyle (FRACTAL) study. Am Heart J 2006; 152:1097-1103.
Gage BF, Waterman AD, Shannon W, Boechler M, Validation of clinical classification schemes for predicting stroke: results from the national registry of atrial fibrillation. JAMA 2001; 285 (22):2864-2870.
Grimm RA. Transoesophageal echocardiography-guided cardioversion of atrial fibrillation. Echocardiography 2000;17:383-392.
Roijer A, Eskilsson J, Olsson B. Transoesophageal-guided cardioversion of atrial fibrillation or flutter. A selection of low risk group for immediate cardioversion. Eur Heart J 2000;20:837-847.
Iqbal MB, Taneja AK, Lip GY, Flather M. Recent developments in atrial fibrillation. BMJ 2005;33:238-243.
Martinez-Marcos FJ, Garcia-Garmendia JL, Ortega-Carpio A et al. Comparison of intravenous flecainide, propafenone, and amiodarone for conversion of acute atrial fibrillation to sinus rhythm. Am J Cardiol 2000;86:950-953.
Joseph AP, Ward MR. A prospective, randomized controlled trial comparing the efficacy and safety of sotalol, amiodarone, and digoxin for the reversion of newonset atrial fibrillation. Ann Emerg Med 2000;36:1-9.
National Collaborating Centre for Chronic Conditions. Atrial Fibrillation: National clinical guideline for management in primary and secondary care. London: Royal College of Physicians 2006. (www.nice.org.uk/CG036).
Gallagher MM, Yap YG, Padula M et al. Arrhythmic complications of electrical cardioversion: relationship to shock energy. Int J Cardiol 2007;123 (2008):307-312.
de Paola AA, Figueiredo E, Sesso R et al. Effectiveness and costs of chemical versus electrical cardioversion of atrial fibrillation. International Journal of Cardiology 2003;88(2-3): 157-163.
Valencia MJ, Climent P, V, Marin O et al. The efficacy of scheduled cardioversion in atrial fibrillation: comparison of two schemes of treatment: electrical versus pharmacological cardioversion. Revista Espanola de Cardiologia 2002; 55(22-3):113-120.
Sulke N., Sayers F., Lip GY. Rhythm control and cardioversion. Heart 2007;93:29-34.
McNamara RL, Tamariz LJ, Segal JB, et al. Management of atrial fibrillation: review of the evidence for the role of pharmacologic therapy, electrical cardioversion, and echocardiography. Ann Intern Med 2003;139:1018.
Farshi R, Kistner D, Sarma JS et al. Ventricular rate control in chronic atrial fibrillation daily activity and programmed exercise: a crossover open-label study of five drug regimens. J Am Coll Cardiol 1999;33:304-310.
Falk RH, Leavitt JI. Digoxin for atrial fibrillation: a drug whose time has gone? Ann Intern Med 1991;114:573-575.
Lairikyengbam S, Anderson M, Davies A. Present treatment options for atrial fibrillation. Postgrad Med J 2003;79:67-73.
Nieuwlaat R., Capucci A. et al. Atrial fibrillation management: a prospective survey in ESC member countries: the Euro Heart Survey on Atrial Fibrillation. Eur Heart J 2005;26(22):2422-2434.
Saxonhouse SJ, Curtis AB. Risks and benefits of rate control versus maintenance of sinus rhythm. Am J Cardiol 2003;91:27D-32D.
Hohnloser SH, Kuck KH, Lilienthal J. Rhythm or rate control in atrial fibrillation Pharmacological Intervention in Atrial Fibrillation (PIAF): a
randomized trial. Lancet 2000;356:1789-1794.
Carlsson J, Miketic S, Windeler J et al. Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study. J Am Cardiol 2003; 41:1690-1696.
Hagens VE, Ranchor AV, Van SE et al. Effect of rate control or rhythm control on quality of life in persistent atrial fibrillation Results from the Rate Control Versus Electrical Cardioversion (RACE) Study. J Am Coll Cardiol 2004;43:241-247.
Sherman DG, Kim SG, Boop BS et al. Relationships between Sinus Rhythm, Treatment, and Survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) study. Circulation 2004;109:1509-1513.
Opolski G, Torbicki A, Kosioor DA et al. Rate control vs rhythm control in patients with nonvalvular persistent atrial fibrillation: the results of Polish How to Treat Chronic Atrial Fibrillation (HOT CAFÉ) Study. Chest 2004; 126:476-486.
Roy D., Talajic M., Nattel S et al. Rhythm control versus rate control for atrial fibrillation and heart failure. N Engl J Med 2008;358(25):2667-2676.
Bardy GH, Lee KL, Mark DB et al. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med 2005; 352:225-237.
Massie BM, Fisher SG, Radford M et al. Effect of amiodarone on clinical status and left ventricular function in patients with congestive heart failure. Circulation 1996; 93:2128-2134.
Cain M., Curtis A. Rhythm Control in Atrial Fibrillation - One Setback after Another. N Engl J Med 2008; 358(25):2725-2727.
Kober L, Torp-Pedersen C., McMurray J et al. Increased Mortality after Dronedarone Therapy for Severe Heart Failure. N Engl J Med 2008;
(25):2678-2687.
Sanofi-Aventis. Dronedarone (Multaq) reduced the incidence and duration of hospitalization in patients with atrial fibrillation. American Heart Association Scientific Sessions; November 11, 2008; New Orleans, LA. Abst
(http://en.sanofi-aventis.com/Images/080515_multaq_en_tcm24-20861.pdf).
Singh B., Connolly S., Crijns H et al. Dronedarone for Maintenance of Sinus Rhythm in Atrial Fibrillation or Flutter. N Engl J Med 2007;357 (10): 987-999.
Davy JM, Herold M et al. Dronedarone for the control of ventricular rate in permanent atrial fibrillation: the efficacy and safety of dronedarone for the control of ventricular rate during atrial fibrillation (ERATO) study. Am Heart J 2008;156(3):527.e1-527.e9.
Shiroshila-Takeshita A, Schram G, Lavole J et al. Effect of simvastatin and antioxidant vitamins on atrial fibrillation promotion by atrial-tachycardia remodeling in dogs. Circulation 2004;110:2313-2319.
Young-Xu Y, Jabbour S, Goldberg R et al. Usefulness of statin drugs in protecting against atrial fibrillation in patients with coronary artery disease. Am J Cardiol 2003;92:1379-1383.
Boos CJ, Lip GY. Targeting the renin-angiotensin-aldosterone system in atrial fibrillation: from pathophysiology to clinical trials. J Hum Hypertens 2005;19:855-859.
Healey JS, Baranchuk A, Crystal E et al. Prevention of atrial fibrillation with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: a meta-analysis. J Am Coll Cardiol 2005;45:1832-1839.
Swedberg K et al. Prevention of atrial fibrillation in symptomatic chronic heart failure by candesartan: results from the CHARM study J Am Coll Cardiol 2004;23(Suppl A):222A.
Maggioni AP et al. Val-HeFT Investigators. Valsartan reduces the incidence of atrial fibrillation in patients with heart failure: results from the Valsartan Heart Failure Trial (Val-HeFT). Am Heart J 2005;149:548-557.
Ehrlich J, Hohnloser SH, Nattel S. Role of angiotensin system and effects of its inhibition in atrial fibrillation: clinical and experimental evidence. Eur Heart Journal 2006; 27, 512-518.
Snow V., Weiss K., LeFevre M et al. Management of Newly Detected Atrial Fibrillation: A Clinical Practice Guideline from the American Academy of Family Physicians Annals of Internal Medicine 2003;139(12):1009-1018
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