Osmotic Myelinolysis – a clinical case report
Keywords:
Central pontine and extrapontine Myelinolysis, osmotic demyelination, hyponatremiaAbstract
The authors describe a case of central pontine and extrapontine Myelinolysis in a man with
alcoholism who presented to hospital with hiponatraemia. Central pontine Myelinolysis is a
demyelination disorder and clinical manifestations include a rapidly evolving flaccid quadriplegia with inability to speak and swallow.
This disorder has been seen in association with
chronic alcoholism and electrolyte derangements. The degree of hyponatraemia or its rapid correction, may lead to this brain lesion.
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