Ácido úrico e Doença cardiovascular
Palavras-chave:
Ácido úrico, Doença Cardiovascular, Factor de riscoResumo
O interesse no ácido úrico como um potencial
factor de risco de Doença Cardiovascular é
abordado em inúmeros artigos de revisão. Parece não haver dúvidas que o ácido úrico é um
factor de risco cardiovascular, ideia essa que
persiste desde há 50 anos. Contudo, a questão
central não é a sua associação com Doença
Cardiovascular, mas se desempenha um papel
causal no desenvolvimento de Doença Cardiovascular.
Tem sido difícil identifi car o papel específico
da hiperuricémia devido à sua associação
com outros factores de risco cardiovascular,
já estabelecidos, como Hipertensão, Diabetes Mellitus, Dislipidémia e Obesidade.
Um melhor conhecimento dos mecanismos patogénicos da hiperuricémia poderão esclarecer
a importância da elevação dos valores séricos de ácido úrico.
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Referências
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